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. 2017 Feb;14(1):33-41.
doi: 10.20892/j.issn.2095-3941.2016.0093.

Epidemiology, etiology, and prevention of esophageal squamous cell carcinoma in China

He Liang  1 , Jin-Hu Fan  1 , You-Lin Qiao  1
Affiliations

Epidemiology, etiology, and prevention of esophageal squamous cell carcinoma in China

He Liang et al. Cancer Biol Med. 2017 Feb.

Abstract

Esophageal cancer is one of the most fatal diseases worldwide mainly because of its rapid progression and poor prognosis. Although the incidence of esophageal adenocarcinoma has markedly risen in North America and Europe in the past several decades, esophageal squamous cell carcinoma is still the predominant subtype of esophageal cancer, especially in China. It accounts for more than 90% of all esophageal squamous cell carcinoma cases in China. Geographical differentiation is one of the most distinctive characteristics of esophageal cancer. The progression, risk factors, and prognosis of these two subtypes of esophageal cancer differ. This study reviews the epidemiology, etiology, and prevention of esophageal squamous cell carcinoma in China, thereby providing systematic references for policy-makers who will decide on issues of esophageal cancer prevention and control.

Keywords: Epidemiology; esophageal squamous cell carcinoma; etiology; prevention; review.

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Figures

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Age-adjusted incidence rates for esophageal cancer according to region and gender in China, 2012.
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Age-adjusted mortality for esophageal cancer according to regions and gender in China, 2012.
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Trends in incidence rates (ASR) for esophageal cancer in China from 2000 to 2011.
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Trends in mortality rates (ASR) for esophageal cancer in China from 2000 to 2011.
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References

    1. International Agency for Research on Cancer. GLOBOCAN 2012, Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012. Geneva: World Health Organization, 2012.

    1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: Globocan 2008. Int J Cancer. 2010;127:2893–917. - PubMed
    1. Enzinger PC, Mayer RJ. Esophageal cancer. N Engl J Med. 2003;349:2241–52. - PubMed
    1. Zhao J, He YT, Zheng RS, Zhang SW, Chen WQ. Analysis of esophageal cancer time trends in China, 1989-2008. Asian Pac J Cancer Prev. 2012;13:4613–7. - PubMed
    1. Chen WQ, Zheng RS, Zhang SW, Zeng HM, Zuo TT, Jia MM, et al. Report of cancer incidence and mortality in China, 2012. China Cancer. 2015;25:1–8.

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