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. 2017 Feb;8(1):86-90.
doi: 10.24171/j.phrp.2017.8.1.12. Epub 2017 Feb 28.

Emergence of Norovirus GII.17-associated Outbreak and Sporadic Cases in Korea from 2014 to 2015

Sunyoung Jung  1 , Bo-Mi Hwang  1 , HyunJu Jung  1 , GyungTae Chung  1 , Cheon-Kwon Yoo  1 , Deog-Yong Lee  1
Affiliations

Emergence of Norovirus GII.17-associated Outbreak and Sporadic Cases in Korea from 2014 to 2015

Sunyoung Jung et al. Osong Public Health Res Perspect. 2017 Feb.

Abstract

Human norovirus are major causative agent of nonbacterial acute gastroenteritis. In general, genogroup (G) II.4 is the most prominent major genotype that circulate in human population and the environment. However, a shift in genotypic trends was observed in Korea in December 2014. In this study, we investigated the trend of norovirus genotype in detail using the database of Acute Diarrhea Laboratory Surveillance (K-EnterNet) in Korea. GII.17 has since become a major contributor to outbreaks of norovirus-related infections and sporadic cases in Korea, although the reason for this shift remain unknown.

Keywords: genogroup II.17; genogroup II.4; norovirus; outbreak.

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Figures

Figure 1
Figure 1
Neighbor-joining phylogenetic tree based on complete VP1 nucleotide sequences (located in ORF2) detected in outbreak cases. Reference sequences were collected from NoroNet and GenBank. Numbers in branches indicate the bootstrap values and outbreak strains classified as genogroup (G) II.17. SE, Seoul; GG, Gyeonggi; DG, Daegu; IC, Incheon.
Figure 2
Figure 2
Prevalence of norovirus genotypes in Korea from 2012 to 2014. A total of 4,964 partial VP1 sequences were used to analyze genotypes and separate them into three groups: genogroup (G) II.4, GII.17, and other norovirus types. (A) Prevalence of norovirus genotypes among outbreaks. The prevalence of GII.17 increased explosively since December 2014. (B) Prevalence of norovirus genotypes among sporadic cases. The GII.17 strain, which had not previously appeared, increased in prevalence since December 2014.
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