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Observational Study
. 2017 Mar;108(3):217-227.
doi: 10.5935/abc.20170028.

Major Depression and Acute Coronary Syndrome-Related Factors

[Article in Portuguese, English]
Jose Henrique Cunha Figueiredo  1 , Nelson Albuquerque de Souza E Silva  1 , Basilio de Bragança Pereira  1 , Glaucia Maria Moraes de Oliveira  1
Affiliations
Observational Study

Major Depression and Acute Coronary Syndrome-Related Factors

[Article in Portuguese, English]
Jose Henrique Cunha Figueiredo et al. Arq Bras Cardiol. 2017 Mar.

Abstract

Background: Major Depressive Disorder (MDD) is one of the most common mental illnesses in psychiatry, being considered a risk factor for Acute Coronary Syndrome (ACS).

Objective: To assess the prevalence of MDD in ACS patients, as well as to analyze associated factors through the interdependence of sociodemographic, lifestyle and clinical variables.

Methods: Observational, descriptive, cross-sectional, case-series study conducted on patients hospitalized consecutively at the coronary units of three public hospitals in the city of Rio de Janeiro over a 24-month period. All participants answered a standardized questionnaire requesting sociodemographic, lifestyle and clinical data, as well as a structured diagnostic interview for the DSM-IV regarding ongoing major depressive episodes. A general log-linear model of multivariate analysis was employed to assess association and interdependence with a significance level of 5%.

Results: Analysis of 356 patients (229 men), with an average and median age of 60 years (SD ± 11.42, 27-89). We found an MDD point prevalence of 23%, and a significant association between MDD and gender, marital status, sedentary lifestyle, Killip classification, and MDD history. Controlling for gender, we found a statistically significant association between MDD and gender, age ≤ 60 years, sedentary lifestyle and MDD history. The log-linear model identified the variables MDD history, gender, sedentary lifestyle, and age ≤ 60 years as having the greatest association with MDD.

Conclusion: Distinct approaches are required to diagnose and treat MDD in young women with ACS, history of MDD, sedentary lifestyle, and who are not in stable relationships.

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Conflict of interest statement

Potential Conflict of Interest

No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1
Graphical representation of the general log-linear model demonstrating the interdependent relationships between the sociodemographic variables and the powers of association without history of major depressive disorder (MDD). Sedent: sedentary lifestyle; SocSup: social support; MarSt: marital status; FI B: family income B (US 615-1230 monthly wages); FI C: family income C (> US 1230 monthly wages); Educat: education level; TobSmo: tobacco smoking.
Figure 2
Figure 2
Graphical representation of the general log-linear model demonstrating the interdependent relationships between the variables examined and the powers of association. MDD: major depressive disorder; MarSt: marital status; Sedent.: sedentary lifestyle; hMDD: history of MDD.
See this image and copyright information in PMC

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