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Review
. 2017 Apr 12:8:400.
doi: 10.3389/fimmu.2017.00400. eCollection 2017.

Clinical Evidence for the Microbiome in Inflammatory Diseases

Ann E Slingerland  1 , Zaker Schwabkey  2 , Diana H Wiesnoski  2 , Robert R Jenq  2   3
Affiliations
Review

Clinical Evidence for the Microbiome in Inflammatory Diseases

Ann E Slingerland et al. Front Immunol. .

Abstract

Clinical evidence is accumulating for a role of the microbiome in contributing to or modulating severity of inflammatory diseases. These studies can be organized by various organ systems involved, as well as type of study approach utilized, whether investigators compared the microbiome of cases versus controls, followed patients longitudinally, or intervened with antibiotics, prebiotics, or bacterial introduction. In this review, we summarize the clinical evidence supporting the microbiome as an important mechanism in the onset and maintenance of inflammation.

Keywords: autoimmune diseases; bacteria; inflammation; microbiome; microbiota.

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Figures

Figure 1
Figure 1
Current strategies of gut microbiota modulation.
See this image and copyright information in PMC

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