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Comment
. 2017 Apr 27;14(5):461-462.
doi: 10.1038/nmeth.4260.

Systems biology guided by XCMS Online metabolomics

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Comment

Systems biology guided by XCMS Online metabolomics

Tao Huan et al. Nat Methods. .
No abstract available

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Figures

Figure 1
Figure 1
Workflow for metabolomic data and pathway analysis using XCMS Online. A metabolite feature table of statistically significant features is generated from standard XCMS processing; these features automatically undergo predictive pathway mapping using a specified biological model. The pathway cloud plot shows dysregulated pathways (blue circles) with increasing statistical significance on the y axis, metabolite overlap on the x axis and total number of metabolites in the pathway represented by the circle radius. The multiscale pathway coverage table presents enriched metabolic pathways with overlapped and total metabolites, genes and proteins. MS/MS data confirm dysregulated pathways by matching metabolite MS/MS spectra with the METLIN database.

Comment on

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