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. 2017 Apr 13;22(15):30508.
doi: 10.2807/1560-7917.ES.2017.22.15.30508.

Emergence of new recombinant noroviruses GII.p16-GII.4 and GII.p16-GII.2, France, winter 2016 to 2017

Maxime Bidalot  1 , Lucie Théry  1 , Jérôme Kaplon  1   2 , Alexis De Rougemont  1   2 , Katia Ambert-Balay  1   2
Affiliations

Emergence of new recombinant noroviruses GII.p16-GII.4 and GII.p16-GII.2, France, winter 2016 to 2017

Maxime Bidalot et al. Euro Surveill. .

Abstract

An early increase in outbreaks of norovirus gastroenteritis characterised at the French National Reference Centre occurred this winter season. They were concurrent with an unusual pattern of circulating strains, with three predominant genotypes: the re-emergent variant GII.P4 2009-GII.4 2012 found in 28% of norovirus outbreaks and two new emergent recombinant strains GII.P16-GII.4 2012 and GII.P16-GII.2 never before observed in France, found in 24% and 14% of norovirus outbreaks, respectively.

Keywords: Norovirus; co-circulation; emergence; gastroenteritis; recombinants.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Cumulative number of norovirus outbreaks investigated at the French National Reference Centre for Gastroenteritis Viruses, France, week 40 to week 3, 2015/16 (n = 55) and 2016/17 (n = 87)
Figure 2
Figure 2
Diversity of norovirus genotypes found at the French National Reference Centre for Gastroenteritis Viruses, France, week 40 to week 3, 2015/16 (n = 61) and 2016/17 (n = 90)
Figure 3
Figure 3
Phylogenetic tree based on the partial nucleotide sequences (287 bp) of the norovirus polymerase gene
Figure 4
Figure 4
Phylogenetic tree based on the partial nucleotide sequences (266 bp) of the norovirus capsid gene
See this image and copyright information in PMC

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