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Case Reports
. 2017 Apr 20;22(16):30517.
doi: 10.2807/1560-7917.ES.2017.22.16.30517.

Three cases of mcr-1-positive colistin-resistant Escherichia coli bloodstream infections in Italy, August 2016 to January 2017

Marta Corbella  1   2 , Bianca Mariani  1   2 , Carolina Ferrari  3 , Francesco Comandatore  4 , Erika Scaltriti  5 , Piero Marone  1 , Patrizia Cambieri  1
Affiliations
Case Reports

Three cases of mcr-1-positive colistin-resistant Escherichia coli bloodstream infections in Italy, August 2016 to January 2017

Marta Corbella et al. Euro Surveill. .

Abstract

We describe three cases of bloodstream infection caused by colistin-resistant Escherichia coli in patients in a tertiary hospital in Italy, between August 2016 and January 2017. Whole genome sequencing detected the mcr-1 gene in three isolated strains belonging to different sequence types (STs). This occurrence of three cases with mcr-1-positive E. coli belonging to different STs in six months suggests a widespread problem in settings where high multidrug resistance is endemic such as in Italy.

Keywords: blood stream infections, surveillance, public health, sepsis; colistin resistance; mcr-1 E.coli.

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Conflict of interest statement

Conflict of interest: None declared.

References

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