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. 2017 Apr 13;22(15):30513.
doi: 10.2807/1560-7917.ES.2017.22.15.30513.

Indistinguishable NDM-producing Escherichia coli isolated from recreational waters, sewage, and a clinical specimen in Ireland, 2016 to 2017

Bláthnaid M Mahon  1 , Carina Brehony  1 , Elaine McGrath  2   3 , James Killeen  1 , Martin Cormican  1   2   3 , Paul Hickey  4 , Shane Keane  4 , Belinda Hanahoe  3 , Ann Dolan  5 , Dearbháile Morris  1
Affiliations

Indistinguishable NDM-producing Escherichia coli isolated from recreational waters, sewage, and a clinical specimen in Ireland, 2016 to 2017

Bláthnaid M Mahon et al. Euro Surveill. .

Abstract

In this study, New Delhi metallo-beta-lactamase (NDM)-producing Enterobacteriaceae were identified in Irish recreational waters and sewage. Indistinguishable NDM-producing Escherichia coli by pulsed-field gel electrophoresis were isolated from sewage, a fresh water stream and a human source. NDM-producing Klebsiella pneumoniae isolated from sewage and seawater in the same area were closely related to each other and to a human isolate. This raises concerns regarding the potential for sewage discharges to contribute to the spread of carbapenemase-producing Enterobacteriaceae.

Keywords: New Delhi metallo-beta-lactamase; antimicrobial resistance; carbapenemase-producing Enterobacteriaceae; recreational waters; wastewater.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Schematic diagram of water and sewage sampling points and their location relative to each other, Ireland, 2016–2017
Figure 2
Figure 2
PFGE analysis of New Delhi metallo-beta-lactamase-producing Escherichia coli isolated from fresh water, sewage and a clinical source in Ireland, 2016–2017 (n = 6 isolates)
Figure 3
Figure 3
PFGE analysis of New Delhi metallo-beta-lactamase-producing Klebsiella pneumoniae isolated from seawater, sewage and a clinical source in Ireland, 2016–2017 (n = 11 isolates)
See this image and copyright information in PMC

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