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Editorial
. 2017 Jul 21;38(28):2198-2200.
doi: 10.1093/eurheartj/ehx219.

CAVD: civilization aortic valve disease

Patrick Mathieu  1 , Benoit J Arsenault  2
Affiliations
Editorial

CAVD: civilization aortic valve disease

Patrick Mathieu et al. Eur Heart J. .
No abstract available

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Figures

Figure 1
Figure 1
Schematic representation of the relationships between the obesogenic environment, adipose tissue, and the aortic valve. CAVD, calcific aortic valve disease; IL-6, interleukin-6; TNF-α, tumour necrosis factor-α.
See this image and copyright information in PMC

Comment on

References

    1. Lindman BR, Clavel MA, Mathieu P, Iung B, Lancellotti P, Otto CM, Pibarot P.. Calcific aortic stenosis. Nat Rev Dis Primers 2016;2:16006. - PMC - PubMed
    1. Thanassoulis G, Campbell CY, Owens DS, Smith JG, Smith AV, Peloso GM, Kerr KF, Pechlivanis S, Budoff MJ, Harris TB, Malhotra R, O’Brien KD, Kamstrup PR, Nordestgaard BG, Tybjaerg-Hansen A, Allison MA, Aspelund T, Criqui MH, Heckbert SR, Hwang SJ, Liu Y, Sjogren M, van der Pals J, Kalsch H, Muhleisen TW, Nothen MM, Cupples LA, Caslake M, Di AE, Danesh J, Rotter JI, Sigurdsson S, Wong Q, Erbel R, Kathiresan S, Melander O, Gudnason V, O’Donnell CJ, Post WS.. Genetic associations with valvular calcification and aortic stenosis. N Engl J Med 2013;368:503–512. - PMC - PubMed
    1. Smith JG, Luk K, Schulz CA, Engert JC, Do R, Hindy G, Rukh G, Dufresne L, Almgren P, Owens DS, Harris TB, Peloso GM, Kerr KF, Wong Q, Smith AV, Budoff MJ, Rotter JI, Cupples LA, Rich S, Kathiresan S, Orho-Melander M, Gudnason V, O’Donnell CJ, Post WS, Thanassoulis G.. Association of low-density lipoprotein cholesterol-related genetic variants with aortic valve calcium and incident aortic stenosis. JAMA 2014;312:1764–1771. - PMC - PubMed
    1. Peltier M, Trojette F, Sarano ME, Grigioni F, Slama MA, Tribouilloy CM.. Relation between cardiovascular risk factors and nonrheumatic severe calcific aortic stenosis among patients with a three-cuspid aortic valve. Am J Cardiol 2003;91:97–99. - PubMed
    1. Rogge BP, Cramariuc D, Lonnebakken MT, Gohlke-Barwolf C, Chambers JB, Boman K, Gerdts E.. Effect of overweight and obesity on cardiovascular events in asymptomatic aortic stenosis: a SEAS substudy (Simvastatin Ezetimibe in Aortic Stenosis). J Am Coll Cardiol 2013;62:1683–1690. - PubMed