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Comparative Study
. 1988 Oct 11;16(19):9323-35.
doi: 10.1093/nar/16.19.9323.

Codon usage in Pseudomonas aeruginosa

S E West  1 , B H Iglewski
Affiliations
Free PMC article
Comparative Study

Codon usage in Pseudomonas aeruginosa

S E West et al. Nucleic Acids Res. .
Free PMC article

Abstract

We have generated a codon usage table for Pseudomonas aeruginosa. Codon usage in P. aeruginosa is extremely biased. In contrast to E. coli and yeast, P. aeruginosa preferentially uses those codons within a synonymous codon group with the strongest predicted codon-anticodon interaction. We were unable to correlate a particular codon usage pattern with predicted levels of mRNA expressivity. The choice of a third base reflects the high guanine plus cytosine content of the P. aeruginosa genome (67.2%) and cytosine is the preferred nucleotide for the third codon position.

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References

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