AIDS-Related Mycoses: Current Progress in the Field and Future Priorities

Darius Armstrong-James¹, Tihana Bicanic², Gordon D Brown³, Jennifer C Hoving⁴, Graeme Meintjes⁴, Kirsten Nielsen⁵; Working Group from the EMBO Workshop on AIDS-Related Mycoses

Affiliations

¹ Fungal Pathogens Laboratory, National Heart and Lung Institute, Imperial College, London SW7 2AY, UK. Electronic address: d.armstrong@imperial.ac.uk.
² Institute of Infection and Immunity, St George's University of London, London SW17 0RS3, UK.
³ Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, 7925, Cape Town, South Africa; MRC Centre for Medical Mycology, Aberdeen Fungal Group, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen AB25 2ZD, UK.
⁴ Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, 7925, Cape Town, South Africa.
⁵ Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, 55455, USA.

PMID: 28454846
PMCID: PMC7549875
DOI: 10.1016/j.tim.2017.02.013

AIDS-Related Mycoses: Current Progress in the Field and Future Priorities

Darius Armstrong-James et al. Trends Microbiol. 2017 Jun.

. 2017 Jun;25(6):428-430.

doi: 10.1016/j.tim.2017.02.013. Epub 2017 Apr 25.

Authors

Darius Armstrong-James¹, Tihana Bicanic², Gordon D Brown³, Jennifer C Hoving⁴, Graeme Meintjes⁴, Kirsten Nielsen⁵; Working Group from the EMBO Workshop on AIDS-Related Mycoses

Affiliations

¹ Fungal Pathogens Laboratory, National Heart and Lung Institute, Imperial College, London SW7 2AY, UK. Electronic address: d.armstrong@imperial.ac.uk.
² Institute of Infection and Immunity, St George's University of London, London SW17 0RS3, UK.
³ Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, 7925, Cape Town, South Africa; MRC Centre for Medical Mycology, Aberdeen Fungal Group, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen AB25 2ZD, UK.
⁴ Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, 7925, Cape Town, South Africa.
⁵ Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, 55455, USA.

PMID: 28454846
PMCID: PMC7549875
DOI: 10.1016/j.tim.2017.02.013

Abstract

Opportunistic fungal infections continue to take an unacceptably heavy toll on the most disadvantaged living with HIV-AIDS, and are a major driver for HIV-related deaths. At the second EMBO Workshop on AIDS-Related Mycoses, clinicians and scientists from around the world reported current progress and key priorities for improving outcomes from HIV-related mycoses.

Keywords: AIDS; HIV; fungal infection; immunity; mortality; translational research.

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References

1. Brown GD (2012) Hidden killers: human fungal infections. Sci. Translat. Med 4, 165rv13 - PubMed
1. Armstrong-James D (2014) A neglected epidemic: fungal infections in HIV/AIDS. Trends Microbiol. 22, 120–127 - PubMed
1. Murray CJ (2012) Global malaria mortality between 1980 and 2010: a systematic analysis. Lancet 379, 413–431 - PubMed
1. Dirlikov E (2015) Global tuberculosis control: toward the 2015 targets and beyond. Ann. Intern. Med. 163, 52–58 - PubMed
1. Meiring S (2016) Prevalence and hospital management of amphotericin B deoxycholate-related toxicities during treatment of HIV-associated cryptococcal meningitis in South Africa . PLoS Negl. Trop. Dis. 10, e0004865. - PMC - PubMed

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AIDS-Related Mycoses: Current Progress in the Field and Future Priorities

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AIDS-Related Mycoses: Current Progress in the Field and Future Priorities

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