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Review
. 2017 Jun;37(2):371-382.
doi: 10.1016/j.cll.2017.01.008. Epub 2017 Mar 27.

Chikungunya Virus

Affiliations
Review

Chikungunya Virus

David M Vu et al. Clin Lab Med. 2017 Jun.

Abstract

For chikungunya virus (CHIKV), the long-term sequelae from infection are yet ill-defined. The prolonged debilitating arthralgia associated with CHIKV infection has tremendous potential for impacting the global economy and should be considered when evaluating the human burden of disease and the allocation of resources. There is much still unknown about CHIKV and the illnesses that it causes. Developing a better understanding of the pathogenesis of CHIKV infection is a priority and forms the basis for developing effective strategies at infection prevention and disease control.

Keywords: Alphavirus; Arbovirus; Chikungunya virus; Togaviridae.

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Figures

Fig. 1
Fig. 1
Transmission cycle of CHIKV in Africa. Nonhuman primates, and possibly other wild animals, serve as reservoirs of the virus. Infected arboreal Aedes mosquitoes bite and infect humans. Infected humans, in turn, infect peridomestic Aedes aegypti, perpetuating the urban cycle of CHIKV transmission.

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