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. 2017 Aug:56:212.e1-212.e3.
doi: 10.1016/j.neurobiolaging.2017.03.014. Epub 2017 Mar 16.

TMEM230 in Parkinson's disease

Laura Ibanez  1 , Umber Dube  2 , John Budde  1 , Kathleen Black  1 , Alexandra Medvedeva  1 , Albert A Davis  3 , Joel S Perlmutter  3 , Bruno A Benitez  4 , Carlos Cruchaga  5
Affiliations

TMEM230 in Parkinson's disease

Laura Ibanez et al. Neurobiol Aging. 2017 Aug.

Abstract

A study on familial Parkinson disease (PD) described 4 variants in the gene TMEM230 (Chr. 20p13) as the cause of PD. The aim of this study was to test if variants in the TMEM230 gene are associated with PD in 2 independent American European data sets. No variants in the TMEM230 region were found associated with PD, age at onset, or cerebrospinal fluid α-synuclein levels.

Keywords: GWAS; Parkinson; TMEM230; WES.

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References

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