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. 2017 Apr;35(1):28-33.
doi: 10.5534/wjmh.2017.35.1.28.

Clinicopathologic Characteristics and Treatment Outcomes of Penile Cancer

Jong Kil Nam  1 , Dong Hoon Lee  1 , Sung Woo Park  1 , Sung Chul Kam  2 , Ki Soo Lee  3 , Tae Hyo Kim  3 , Taek Sang Kim  4 , Cheol Kyu Oh  5 , Hyun Jun Park  6 , Tae Nam Kim  7
Affiliations

Clinicopathologic Characteristics and Treatment Outcomes of Penile Cancer

Jong Kil Nam et al. World J Mens Health. 2017 Apr.

Abstract

Purpose: The aim of this study was to assess the clinicopathologic characteristics of penile cancer, including patterns of therapy, oncologic results, and survival.

Materials and methods: Between January 2005 and July 2015, 71 patients at 6 institutions who had undergone penectomy or penile biopsy were enrolled. Their medical records were reviewed to identify the mode of therapy, pathology reports, and cancer-specific survival (CSS) rate.

Results: Clinicopathologic and outcome information was available for 52 male patients (mean age, 64.3 years; mean follow-up, 61.4 months). At presentation, 17 patients were node-positive, and 4 had metastatic disease. Management was partial penectomy in 34 patients, total penectomy in 12 patients, and chemotherapy or radiotherapy in 6 patients. The pathology reports were squamous cell carcinoma in 50 patients and other types of carcinoma in the remaining 2 patients. Kaplan-Meier survival analysis showed a 5-year CSS rate of 84.0%. In univariate and multivariate analyses, the American Joint Committee on Cancer (AJCC) stage and pathologic grade were associated with survival.

Conclusions: Partial penectomy was the most common treatment of penile lesions. The oncologic outcomes were good, with a 5-year CSS of 84.0%. The AJCC stage and pathologic grade were independent prognostic factors for survival.

Keywords: Penile neoplasms; Prognosis; Treatment outcome.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1. Kaplan-Meier estimated survival rate in available 52 patients was 84.0% at 5-year.
Fig. 2
Fig. 2. Kaplan-Meier estimated survival rate according to American Joint Committee on Cancer (AJCC) stage (A) and pathologic grade (B).
See this image and copyright information in PMC

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