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Editorial
. 2017 May;56(5):553-555.
doi: 10.1165/rcmb.2017-0023ED.

Impaired AMPK Activity Drives Age-Associated Acute Lung Injury after Hemorrhage

Brian D Southern  1 , Rachel G Scheraga  1 , Mitchell A Olman  1
Affiliations
Editorial

Impaired AMPK Activity Drives Age-Associated Acute Lung Injury after Hemorrhage

Brian D Southern et al. Am J Respir Cell Mol Biol. 2017 May.
No abstract available

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Figures

Figure 1.
Figure 1.
Working model for the role of 5′ adenosine monophosphate–activated protein kinase (AMPK) in aging and hemorrhage-induced lung injury. Hemorrhage and aging conspire to reduce AMPK phosphorylation, leading to the increased inflammation and impaired mitochondrial regulation that drives lung injury. NF-κB, nuclear factor-κB; PCG-1α, peroxisome proliferator-activated receptor-γ coactivator 1-α; SIRT1, sirtuin 1.
See this image and copyright information in PMC

Comment on

  • doi: 10.1165/rcmb.2016-0118OC

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