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Affiliations

¹ Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pa. Electronic address: Scott.canna@chp.edu.
² Division of Rheumatology, Department of Internal Medicine Specialties, University Hospitals of Geneva, Geneva, Switzerland.
³ Translational Autoinflammatory Disease Section, Intramural Research Program, NIH, Bethesda, Md.
⁴ Children's Hospital of Philadelphia, Philadelphia, Pa.
⁵ AB2Bio, Ltd, Lausanne, Switzerland.

Comment

Scott W Canna et al. J Allergy Clin Immunol. 2017 Jul.

. 2017 Jul;140(1):316-317.

doi: 10.1016/j.jaci.2017.03.016. Epub 2017 Apr 29.

¹ Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pa. Electronic address: Scott.canna@chp.edu.
² Division of Rheumatology, Department of Internal Medicine Specialties, University Hospitals of Geneva, Geneva, Switzerland.
³ Translational Autoinflammatory Disease Section, Intramural Research Program, NIH, Bethesda, Md.
⁴ Children's Hospital of Philadelphia, Philadelphia, Pa.
⁵ AB2Bio, Ltd, Lausanne, Switzerland.

No abstract available

Comment on

Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition.
Canna SW, Girard C, Malle L, de Jesus A, Romberg N, Kelsen J, Surrey LF, Russo P, Sleight A, Schiffrin E, Gabay C, Goldbach-Mansky R, Behrens EM. Canna SW, et al. J Allergy Clin Immunol. 2017 May;139(5):1698-1701. doi: 10.1016/j.jaci.2016.10.022. Epub 2016 Nov 19. J Allergy Clin Immunol. 2017. PMID: 27876626 Free PMC article.
IL-18 binding protein reverses the life-threatening hyperinflammation of a baby with the NLRC4 mutation.
Novick D, Dinarello CA. Novick D, et al. J Allergy Clin Immunol. 2017 Jul;140(1):316. doi: 10.1016/j.jaci.2017.02.037. Epub 2017 Apr 28. J Allergy Clin Immunol. 2017. PMID: 28457594 No abstract available.