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Comment
. 2017 May;7(5):456-458.
doi: 10.1158/2159-8290.CD-17-0268.

A Road Map for Precision Cancer Medicine Using Personalized Models

Gabriele Picco  1 , Mathew J Garnett  2
Affiliations
Comment

A Road Map for Precision Cancer Medicine Using Personalized Models

Gabriele Picco et al. Cancer Discov. 2017 May.

Abstract

<b/> A study by Pauli and colleagues in this issue of Cancer Discovery describes the creation of a precision cancer platform for patients with advanced disease, integrating DNA sequencing of patient tumors with the generation of patient-derived organoids and xenografts. They propose the use of this platform for drug testing to nominate therapeutic options for individual patients and for therapeutic biomarker discovery. Cancer Discov; 7(5); 456-8. ©2017 AACRSee related article by Pauli et al., p. 462.

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  • Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine.
    Pauli C, Hopkins BD, Prandi D, Shaw R, Fedrizzi T, Sboner A, Sailer V, Augello M, Puca L, Rosati R, McNary TJ, Churakova Y, Cheung C, Triscott J, Pisapia D, Rao R, Mosquera JM, Robinson B, Faltas BM, Emerling BE, Gadi VK, Bernard B, Elemento O, Beltran H, Demichelis F, Kemp CJ, Grandori C, Cantley LC, Rubin MA. Pauli C, et al. Cancer Discov. 2017 May;7(5):462-477. doi: 10.1158/2159-8290.CD-16-1154. Epub 2017 Mar 22. Cancer Discov. 2017. PMID: 28331002 Free PMC article.

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