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Case Reports
. 2016 Apr 30;11(1):18-21.
eCollection 2016.

Multiple concurrent primary extramammary Paget's disease

M Leelavathi  1 , M N Norazirah  2 , A P Nur Amirah  3
Affiliations
Case Reports

Multiple concurrent primary extramammary Paget's disease

M Leelavathi et al. Malays Fam Physician. .

Abstract

Extramammary Paget's disease (EMPD) is a rare malignant disorder of the skin, which was described in as early as the nineteenth century. EMPD usually occurs as a single lesion in the apocrine sweat gland-bearing skin with abundant hair follicles. Here, we present an elderly man who suffered from a non-resolving chronic genital pruritus for 8 months. Initially, he was managed for recurrent fungal infection and eczema. Later, a diagnosis of the rare condition multiple primary EMPD was made based on the histopathology findings and appropriate treatment was given.

Keywords: Axilla; Paget's disease; extramammary; scrotum; vulva.

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Figures

Figure 1.
Figure 1.
Genital lesion: erythematous plaque with focal areas of erosions involving the skin of the scrotum, the penis and the adjacent suprapubic area
Figure 2.
Figure 2.
Left axilla: well-demarcated brownish patch with darker central areas
Figure 3.
Figure 3.
Intra-epidermal proliferation of Paget's cell in nests [10× magnification, haematoxylin and eosin (H&E)]
Figure 4.
Figure 4.
The Paget's cell stained positive for cytokeratin 7
Figure 5.
Figure 5.
The Paget's cells stained negative for p63
See this image and copyright information in PMC

References

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