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Published Erratum
. 2017 May 3;13(5):e1006368.
doi: 10.1371/journal.ppat.1006368. eCollection 2017 May.

Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial

Sergio Serrano-Villar, Talia Sainz, Zhong-Min Ma, Netanya S Utay, Tae Wook-Chun, Surinder Mann, Angela D Kashuba, Basile Siewe, Anthony Albanese, Paolo Troia-Cancio, Elizabeth Sinclair, Anoma Somasunderam, Tammy Yotter, Steven G Deeks, Alan Landay, Richard B Pollard, Christopher J Miller, Santiago Moreno, David M Asmuth
Published Erratum

Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial

Sergio Serrano-Villar et al. PLoS Pathog. .

Abstract

[This corrects the article DOI: 10.1371/journal.ppat.1005381.].

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Figures

Fig 7
Fig 7. Tissue drug distribution.
Panels A-B. Rectum/plasma (A) and duodenum/plasma (B) drug concentration ratios. The tissue concentrations converted to ng/mL assuming a tissue density of 1.06 g/mL. Maraviroc reached the highest distribution to rectum and duodenum (all P<0.005). Panel C-E. Correlations between plasma, rectum and duodenal levels of EFV (C),MVC(D) and RAL (E). MVC plasma levels correlated better with tissue levels than RAL or EFV.
Fig 9
Fig 9
Absolute concentrations in each compartment of efavirenz (A), maraviroc (B) and raltegravir (C) related to the IC50 for HIV-1 replication. The tissue concentrations converted to ng/mL assuming a tissue density of 1.06 g/mL.
See this image and copyright information in PMC

Erratum for

References

    1. Serrano-Villar S, Sainz T, Ma Z-M, Utay NS, Wook-Chun T, Mann S, et al. (2016) Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog 12(1): e1005381 doi:10.1371/journal.ppat.1005381 - DOI - PMC - PubMed

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