Measuring inflammation in IBD with an OSM-ostat

doi:10.1126/scitranslmed.aan3777

Comment

. 2017 May 3;9(388):eaan3777.

doi: 10.1126/scitranslmed.aan3777.

Measuring inflammation in IBD with an OSM-ostat

Tiffany C Scharschmidt¹

Affiliations

PMID: 28469037
DOI: 10.1126/scitranslmed.aan3777

Comment

Measuring inflammation in IBD with an OSM-ostat

Tiffany C Scharschmidt. Sci Transl Med. 2017.

. 2017 May 3;9(388):eaan3777.

doi: 10.1126/scitranslmed.aan3777.

Author

Tiffany C Scharschmidt¹

Affiliation

¹ Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA. Email: tiffany.scharschmidt@ucsf.edu.

PMID: 28469037
DOI: 10.1126/scitranslmed.aan3777

Abstract

Oncostatin M is elevated in inflammatory bowel disease, wherein it may promote intestinal stroma cell inflammation and predict nonresponsiveness to anti-TNF therapy.

PubMed Disclaimer

Comment on

Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease.
West NR, Hegazy AN, Owens BMJ, Bullers SJ, Linggi B, Buonocore S, Coccia M, Görtz D, This S, Stockenhuber K, Pott J, Friedrich M, Ryzhakov G, Baribaud F, Brodmerkel C, Cieluch C, Rahman N, Müller-Newen G, Owens RJ, Kühl AA, Maloy KJ, Plevy SE; Oxford IBD Cohort Investigators; Keshav S, Travis SPL, Powrie F. West NR, et al. Nat Med. 2017 May;23(5):579-589. doi: 10.1038/nm.4307. Epub 2017 Apr 3. Nat Med. 2017. PMID: 28368383 Free PMC article.

Similar articles

Oncostatin M Induces a Pro-inflammatory Phenotype in Intestinal Subepithelial Myofibroblasts.
Kokkotis G, Filidou E, Tarapatzi G, Spathakis M, Kandilogiannakis L, Dovrolis N, Arvanitidis K, Drygiannakis I, Valatas V, Vradelis S, Manolopoulos VG, Paspaliaris V, Kolios G, Bamias G. Kokkotis G, et al. Inflamm Bowel Dis. 2024 Nov 4;30(11):2162-2173. doi: 10.1093/ibd/izae098. Inflamm Bowel Dis. 2024. PMID: 38717842
Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease.
West NR, Hegazy AN, Owens BMJ, Bullers SJ, Linggi B, Buonocore S, Coccia M, Görtz D, This S, Stockenhuber K, Pott J, Friedrich M, Ryzhakov G, Baribaud F, Brodmerkel C, Cieluch C, Rahman N, Müller-Newen G, Owens RJ, Kühl AA, Maloy KJ, Plevy SE; Oxford IBD Cohort Investigators; Keshav S, Travis SPL, Powrie F. West NR, et al. Nat Med. 2017 May;23(5):579-589. doi: 10.1038/nm.4307. Epub 2017 Apr 3. Nat Med. 2017. PMID: 28368383 Free PMC article.
TNF receptor associated factor 5 controls oncostatin M-mediated lung inflammation.
Machiyama T, So T, Okuyama Y, Kobayashi S, Phung HT, Asao A, Harigae H, Ishii N. Machiyama T, et al. Biochem Biophys Res Commun. 2018 May 15;499(3):544-550. doi: 10.1016/j.bbrc.2018.03.186. Epub 2018 Apr 2. Biochem Biophys Res Commun. 2018. PMID: 29596835
Oncostatin M as a new diagnostic, prognostic and therapeutic target in inflammatory bowel disease (IBD).
Verstockt S, Verstockt B, Vermeire S. Verstockt S, et al. Expert Opin Ther Targets. 2019 Nov;23(11):943-954. doi: 10.1080/14728222.2019.1677608. Epub 2019 Oct 15. Expert Opin Ther Targets. 2019. PMID: 31587593 Review.
The oncostatin M-stromal cell axis in health and disease.
West NR, Owens BMJ, Hegazy AN. West NR, et al. Scand J Immunol. 2018 Sep;88(3):e12694. doi: 10.1111/sji.12694. Epub 2018 Jul 4. Scand J Immunol. 2018. PMID: 29926972 Review.

See all similar articles

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions

LinkOut - more resources

Full Text Sources
- Atypon
Other Literature Sources
- scite Smart Citations

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Measuring inflammation in IBD with an OSM-ostat

Affiliation

Measuring inflammation in IBD with an OSM-ostat

Author

Affiliation

Abstract

Comment on

Similar articles

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Abstract

Comment on

Similar articles

Publication types

MeSH terms

Substances

Related information

LinkOut - more resources

Full Text Sources

Other Literature Sources