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Case Reports
. 2017 Mar 21;5(5):616-620.
doi: 10.1002/ccr3.788. eCollection 2017 May.

Myopericarditis in a patient with hepatitis C and cryoglobulinemic renal disease

Mohamoud A Ali  1 , Waqas Z Kayani  2 , Bradley M Linzie  3 , Gopal V Punjabi  4 , James B Wetmore  5   6
Affiliations
Case Reports

Myopericarditis in a patient with hepatitis C and cryoglobulinemic renal disease

Mohamoud A Ali et al. Clin Case Rep. .

Abstract

Although cryoglobulinemia is a well-appreciated complication of hepatitis C (HC), myopericarditis with resulting pericardial effusion is extremely rare, especially in the absence of a liver transplant. In patients with HC, pericardial effusion with impending tamponade can be a florid and potentially life-threatening manifestation of multiorgan cryoglobulinemic disease.

Keywords: Cryoglobulinemia; hepatitis C; membranoproliferative glomerulonephritis; myocarditis; pericarditis; vasculitis.

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Figures

Figure 1
Figure 1
(A) Presence of a large, circumferential pericardial effusion with evidence for early diastolic collapse (arrow) of the right ventricle, consistent with impending tamponade physiology. (B) Phase sensitive inversion recovery sequence obtained 8 min after infusion of intravenous gadolinium. Short‐axis plane showed diffuse pericardial thickening and punctate subepicardial foci of delayed enhancement in the inferolateral wall.
Figure 2
Figure 2
(A) Glomeruli demonstrated diffuse endocapillary proliferation and PAS‐positive hyaline thrombi. (B) Electron microscopy showed curvilinear substructure to the electron‐dense intraluminal and mesangial deposits characteristic of cryoglobulinemic glomerulonephritis.
See this image and copyright information in PMC

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