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Review
. 2017 May 5;18(5):983.
doi: 10.3390/ijms18050983.

The Use of "Omics" in Lactation Research in Dairy Cows

Shanshan Li  1 , Quanjuan Wang  2 , Xiujuan Lin  3 , Xiaolu Jin  4 , Lan Liu  5 , Caihong Wang  6 , Qiong Chen  7 , Jianxin Liu  8 , Hongyun Liu  9
Affiliations
Review

The Use of "Omics" in Lactation Research in Dairy Cows

Shanshan Li et al. Int J Mol Sci. .

Abstract

"Omics" is the application of genomics, transcriptomics, proteomics, and metabolomics in biological research. Over the years, tremendous amounts of biological information has been gathered regarding the changes in gene, mRNA and protein expressions as well as metabolites in different physiological conditions and regulations, which has greatly advanced our understanding of the regulation of many physiological and pathophysiological processes. The aim of this review is to comprehensively describe the advances in our knowledge regarding lactation mainly in dairy cows that were obtained from the "omics" studies. The "omics" technologies have continuously been preferred as the technical tools in lactation research aiming to develop new nutritional, genetic, and management strategies to improve milk production and milk quality in dairy cows.

Keywords: genomics; lactation; metabolomics; proteomics; transcriptomics.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The methods applied in omics research and their applications in lactation research. Abbreviations: 2-DE, two-dimensional electrophoresis; MS, mass spectrometry; iTRAQ, isobaric tags for absolute and relative quantification; GC-MS, gas chromatography-mass spectrometry; NMR, nuclear magnetic resonance. The arrows refer to the reactive direction.
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