Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 May 5;18(5):983.
doi: 10.3390/ijms18050983.

The Use of "Omics" in Lactation Research in Dairy Cows

Shanshan Li  1 , Quanjuan Wang  2 , Xiujuan Lin  3 , Xiaolu Jin  4 , Lan Liu  5 , Caihong Wang  6 , Qiong Chen  7 , Jianxin Liu  8 , Hongyun Liu  9
Affiliations
Review

The Use of "Omics" in Lactation Research in Dairy Cows

Shanshan Li et al. Int J Mol Sci. .

Abstract

"Omics" is the application of genomics, transcriptomics, proteomics, and metabolomics in biological research. Over the years, tremendous amounts of biological information has been gathered regarding the changes in gene, mRNA and protein expressions as well as metabolites in different physiological conditions and regulations, which has greatly advanced our understanding of the regulation of many physiological and pathophysiological processes. The aim of this review is to comprehensively describe the advances in our knowledge regarding lactation mainly in dairy cows that were obtained from the "omics" studies. The "omics" technologies have continuously been preferred as the technical tools in lactation research aiming to develop new nutritional, genetic, and management strategies to improve milk production and milk quality in dairy cows.

Keywords: genomics; lactation; metabolomics; proteomics; transcriptomics.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The methods applied in omics research and their applications in lactation research. Abbreviations: 2-DE, two-dimensional electrophoresis; MS, mass spectrometry; iTRAQ, isobaric tags for absolute and relative quantification; GC-MS, gas chromatography-mass spectrometry; NMR, nuclear magnetic resonance. The arrows refer to the reactive direction.
See this image and copyright information in PMC

References

    1. Ayadi M., Caja G., Such X., Knight C.H. Effect of omitting one milking weekly on lactational performances and morphological udder changes in dairy cows. J. Dairy Sci. 2003;86:2352–2358. doi: 10.3168/jds.S0022-0302(03)73828-4. - DOI - PubMed
    1. Whittlestone W.G. Intramammary pressure changes in the lactating cow: I. Changes during the milking process. J. Dairy Res. 1955;22:319–326. doi: 10.1017/S0022029900007822. - DOI
    1. Akers R.M. Lactation physiology: A ruminant animal perspective. Protoplasma. 1990;159:96–111. doi: 10.1007/BF01322593. - DOI
    1. Bionaz M., Loor J.J. Gene networks driving bovine milk fat synthesis during the lactation cycle. BMC Genom. 2008;9:366. doi: 10.1186/1471-2164-9-366. - DOI - PMC - PubMed
    1. Bionaz M., Loor J.J. Gene networks driving bovine mammary protein synthesis during the lactation cycle. Bioinform. Biol. Insights. 2011;5:83–98. doi: 10.4137/BBI.S7003. - DOI - PMC - PubMed

LinkOut - more resources