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Comment
. 2017 May 4;20(5):581-582.
doi: 10.1016/j.stem.2017.04.001.

Synthetic Embryos: Windows into Mammalian Development

Aryeh Warmflash  1
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Synthetic Embryos: Windows into Mammalian Development

Aryeh Warmflash. Cell Stem Cell. .
Free article

Abstract

Mammalian embryonic stem cells (ESCs) can self-organize in vitro, but whether they can recreate early embryonic morphogenesis is unclear. Harrison et al. recently demonstrate in Science that 3D co-cultures of mouse ESCs and trophoblast stem cells self-organize into embryo-like structures that recreate many features of early mouse development.

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