Clinical Trial
A comparative study of the effect of three doses of nedocromil sodium and placebo given by pressurized aerosol to asthmatics with exercise-induced bronchoconstriction
Affiliations
- PMID: 2847600
Item in Clipboard
Clinical Trial
A comparative study of the effect of three doses of nedocromil sodium and placebo given by pressurized aerosol to asthmatics with exercise-induced bronchoconstriction
Ann Allergy.
1988 Nov.
Abstract
The effect of placebo and 1 mg, 4 mg, or 8 mg nedocromil sodium, administered 60 minutes prior to treadmill challenge, was determined in a double-blind study of 12 adult asthmatics with reproducible exercise-induced bronchoconstriction. All nedocromil sodium treatments gave significantly smaller falls in PEFR than placebo. Four and 8 mg gave significantly greater protection than 1 mg.
Similar articles
-
Effects of nedocromil sodium, cromolyn sodium, and a placebo in exercise-induced asthma.Ann Allergy. 1992 Feb;68(2):143-8. Ann Allergy. 1992. PMID: 1310834 Clinical Trial.
-
Exercise-induced asthma: comparison of cromoglycate powder and aerosol four hours before exercise.N Z Med J. 1984 Jan 11;97(747):6-8. N Z Med J. 1984. PMID: 6419184
-
Comparison of nedocromil sodium and sodium cromoglycate administered by pressurized aerosol, with and without a spacer device in exercise-induced asthma in children.Eur Respir J. 1993 Apr;6(4):523-6. Eur Respir J. 1993. PMID: 8387933 Clinical Trial.
-
Clinical evaluation of nedocromil sodium in asthma.Eur J Respir Dis Suppl. 1986;147:149-59. Eur J Respir Dis Suppl. 1986. PMID: 3021489 Review.
-
Nedocromil sodium versus sodium cromoglycate in treatment of exercise-induced bronchoconstriction: a systematic review.Eur Respir J. 2001 Jan;17(1):39-45. doi: 10.1183/09031936.01.17100390. Eur Respir J. 2001. PMID: 11307752
Cited by
-
Nedocromil sodium for preventing exercise-induced bronchoconstriction.Cochrane Database Syst Rev. 2000;2002(2):CD001183. doi: 10.1002/14651858.CD001183. Cochrane Database Syst Rev. 2000. Update in: Cochrane Database Syst Rev. 2002;(1):CD001183. doi: 10.1002/14651858.CD001183. PMID: 10796616 Free PMC article. Updated.
-
Nedocromil sodium. An updated review of its pharmacological properties and therapeutic efficacy in asthma.Drugs. 1993 May;45(5):693-715. doi: 10.2165/00003495-199345050-00007. Drugs. 1993. PMID: 7686465 Review.