[Is the Arg-Gly-Asp sequence the site for foot-and-mouth disease virus binding with cell receptor?]
[Article in
Russian]
- PMID: 2847760
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[Is the Arg-Gly-Asp sequence the site for foot-and-mouth disease virus binding with cell receptor?]
[Article in
Russian]
Bioorg Khim.
1988 Jul.
Abstract
The Arg-Gly-Asp sequence is being found in an increasing wide range of proteins with "adhesive" function. Studying a series of synthetic peptide fragments of VP1 protein of FMDV, we showed that peptides containing the Arg-Gly-Asp sequence, but not control peptides, inhibited FMDV binding to pig kidney cells in vitro, thus indicating participation of that sequence in FMDV binding to host cells.
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