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Case Reports
. 2017 Apr-Jun;9(2):211-213.
doi: 10.4103/UA.UA_10_16.

Zoon's balanitis treated with topical tacrolimus

Sudarshan O Daga  1 , Vinayak G Wagaskar  1 , Snehal F Jumnake  2 , Sujata K Patwardhan  1
Affiliations
Case Reports

Zoon's balanitis treated with topical tacrolimus

Sudarshan O Daga et al. Urol Ann. 2017 Apr-Jun.

Abstract

Zoon's balanitis is an asymptomatic lesion that requires histopathological examination of involved tissue for confirmation of diagnosis. Till today, circumcision is considered as the treatment of choice as topical medical therapy is insufficient to cure the disease and also there was a risk of recurrence after discontinuation of therapy. Herein, we have treated the Zoon's balanitis with 0.1% topical tacrolimus with complete resolution of the lesion in 6 weeks. Hence, we think topical tacrolimus therapy should be considered as an alternative to circumcision in the treatment of Zoon's balanitis.

Keywords: Circumcision; plasma cells; prepuce.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Well demarcated reddish nodular lesion involving inner preputial and adjacent part of glans
Figure 2
Figure 2
Microscopic examination of tissue bit showing focal inflammation in surface epithelium and thinned out epidermis (H and E, ×40)
Figure 3
Figure 3
Microscopic examination of tissue bit showing sub-epidermal connective tissue with dense lympho-plasmocytic inflammation with predominant plasma cells (H and E, ×100)
Figure 4
Figure 4
Lesion after tacrolimus application
Figure 5
Figure 5
Preputial lesion after tacrolimus application
See this image and copyright information in PMC

References

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