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Review
. 2017 Aug;26(1):38-52.
doi: 10.15265/IY-2017-007. Epub 2017 Sep 11.

Clinical Data Reuse or Secondary Use: Current Status and Potential Future Progress

S M Meystre, C Lovis, T Bürkle, G Tognola, A Budrionis, C U Lehmann
Review

Clinical Data Reuse or Secondary Use: Current Status and Potential Future Progress

S M Meystre et al. Yearb Med Inform. 2017 Aug.

Abstract

Objective: To perform a review of recent research in clinical data reuse or secondary use, and envision future advances in this field. Methods: The review is based on a large literature search in MEDLINE (through PubMed), conference proceedings, and the ACM Digital Library, focusing only on research published between 2005 and early 2016. Each selected publication was reviewed by the authors, and a structured analysis and summarization of its content was developed. Results: The initial search produced 359 publications, reduced after a manual examination of abstracts and full publications. The following aspects of clinical data reuse are discussed: motivations and challenges, privacy and ethical concerns, data integration and interoperability, data models and terminologies, unstructured data reuse, structured data mining, clinical practice and research integration, and examples of clinical data reuse (quality measurement and learning healthcare systems). Conclusion: Reuse of clinical data is a fast-growing field recognized as essential to realize the potentials for high quality healthcare, improved healthcare management, reduced healthcare costs, population health management, and effective clinical research.

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Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

Figures

Fig. 1 Example of data extraction process from operative systems and source terminologies into an i2b2 research database infrastructure. Figure adapted from the IDRT project [ 107 ]
Fig. 1 Example of data extraction process from operative systems and source terminologies into an i2b2 research database infrastructure. Figure adapted from the IDRT project [ 107 ]
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Fig. 2 Requirement for syntactic and semantic mapping when transferring data from one Electronic Patient Record (EPR) to another (adapted from [ 112 ])
Fig. 2 Requirement for syntactic and semantic mapping when transferring data from one Electronic Patient Record (EPR) to another (adapted from [ 112 ])
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See this image and copyright information in PMC

References

    1. U.S. Department of Health and Human Services Doctors and hospitals’ use of health IT more than doubles since 2012. Available from:http://www.hhs.gov/news/press/2013pres/05/20130522a.html
    1. Schoen C, Osborn R, Doty MM, Squires D, Peugh J, Applebaum S.A survey of primary care physicians in eleven countries, 2009: perspectives on care, costs, and experiences Health Affairs Project HOPE - The People-to-People Health Foundation, Inc 2009. Nov;2806w1171–83. - PubMed
    1. Safran C, Bloomrosen M, Hammond WE, Labkoff S, Markel-Fox S, Tang PCet al. Toward a national framework for the secondary use of health data: an American Medical Informatics Association White Paper J Am Med Inform Assoc 2007. Jan;14011–9. - PMC - PubMed
    1. National Research Council (US) Committee on A Framework for Developing a New Taxonomy of Disease . Washington (DC): National Academies Press (US); 2011. Toward Precision Medicine: Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease. - PubMed
    1. National Committee on Vital and Health Statistics Information for health: A strategy for building the National Health Information InfrastructureAvailable from:aspe.hhs.gov/sp/nhii/documents/NHIIReport2001/toc.htm