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. 2016 Nov 30:10:636-645.
doi: 10.2174/1874325001610010636. eCollection 2016.

Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections

Yusuf H Mirza  1 , Rosamond Tansey  1 , Mohamed Sukeik  2 , Mohammed Shaath  3 , Fares Sami Haddad  1
Affiliations

Biofilm and the Role of Antibiotics in the Treatment of Periprosthetic Hip and Knee Joint Infections

Yusuf H Mirza et al. Open Orthop J. .

Abstract

An increasing demand for lower limb arthroplasty will lead to a proportionate increase in the need for revision surgery. A notable proportion of revision surgery is secondary to periprosthetic joint infections (PJI). Diagnosing and eradicating PJI can form a very difficult challenge. An important cause of PJI is the formation of a bacterial biofilm on the implant surface. Our review article seeks to describe biofilms; their definitions and formation, common causative bacteria, prophylactic and therapeutic antibiotic therapy.

Keywords: Antibiotics; Biofilm; Periprosthetic joint infection; Total hip arthroplasty; Total knee arthroplasty.

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