Comment on

• Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions.

  Kim YB, Komor AC, Levy JM, Packer MS, Zhao KT, Liu DR. Kim YB, et al. Nat Biotechnol. 2017 Apr;35(4):371-376. doi: 10.1038/nbt.3803. Epub 2017 Feb 13. Nat Biotechnol. 2017. PMID: 28191901 Free PMC article.
• Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion.

  Zong Y, Wang Y, Li C, Zhang R, Chen K, Ran Y, Qiu JL, Wang D, Gao C. Zong Y, et al. Nat Biotechnol. 2017 May;35(5):438-440. doi: 10.1038/nbt.3811. Epub 2017 Feb 27. Nat Biotechnol. 2017. PMID: 28244994
• Highly efficient RNA-guided base editing in mouse embryos.

  Kim K, Ryu SM, Kim ST, Baek G, Kim D, Lim K, Chung E, Kim S, Kim JS. Kim K, et al. Nat Biotechnol. 2017 May;35(5):435-437. doi: 10.1038/nbt.3816. Epub 2017 Feb 27. Nat Biotechnol. 2017. PMID: 28244995
• Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion.

  Shimatani Z, Kashojiya S, Takayama M, Terada R, Arazoe T, Ishii H, Teramura H, Yamamoto T, Komatsu H, Miura K, Ezura H, Nishida K, Ariizumi T, Kondo A. Shimatani Z, et al. Nat Biotechnol. 2017 May;35(5):441-443. doi: 10.1038/nbt.3833. Epub 2017 Mar 27. Nat Biotechnol. 2017. PMID: 28346401
• Genome-wide target specificities of CRISPR RNA-guided programmable deaminases.

  Kim D, Lim K, Kim ST, Yoon SH, Kim K, Ryu SM, Kim JS. Kim D, et al. Nat Biotechnol. 2017 May;35(5):475-480. doi: 10.1038/nbt.3852. Epub 2017 Apr 10. Nat Biotechnol. 2017. PMID: 28398345