Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2017 Jun;27(6):391-392.
doi: 10.1016/j.tcb.2017.04.003. Epub 2017 May 6.

Mitochondria Bioenergetic and Cognitive Functions: The Cannabinoid Link

Giacomo Mancini  1 , Tamas L Horvath  2
Affiliations
Comment

Mitochondria Bioenergetic and Cognitive Functions: The Cannabinoid Link

Giacomo Mancini et al. Trends Cell Biol. 2017 Jun.

Abstract

Despite the well-known role of chronic mitochondrial dysfunction in the pathophysiology of the brain, the impact of acute impairment of mitochondrial activity by cannabinoids on higher brain functions is unknown. In a recent paper in Nature, Hebert-Chatelain et al. elegantly uncovered the essential role that bioenergetic processes have in the regulation of higher brain functions, such as learning and memory.

Keywords: brain; cannabinoid receptor 1; learning; memory; mitochondria.

PubMed Disclaimer

Comment on

  • A cannabinoid link between mitochondria and memory.
    Hebert-Chatelain E, Desprez T, Serrat R, Bellocchio L, Soria-Gomez E, Busquets-Garcia A, Pagano Zottola AC, Delamarre A, Cannich A, Vincent P, Varilh M, Robin LM, Terral G, García-Fernández MD, Colavita M, Mazier W, Drago F, Puente N, Reguero L, Elezgarai I, Dupuy JW, Cota D, Lopez-Rodriguez ML, Barreda-Gómez G, Massa F, Grandes P, Bénard G, Marsicano G. Hebert-Chatelain E, et al. Nature. 2016 Nov 24;539(7630):555-559. doi: 10.1038/nature20127. Epub 2016 Nov 9. Nature. 2016. PMID: 27828947

LinkOut - more resources