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. 2017 Oct 1;34(19):2706-2712.
doi: 10.1089/neu.2017.4970. Epub 2017 Jul 19.

Prevalence of Abnormal Magnetic Resonance Imaging Findings in Children with Persistent Symptoms after Pediatric Sports-Related Concussion

Robert H Bonow  1   2 , Seth D Friedman  3 , Francisco A Perez  4 , Richard G Ellenbogen  2 , Samuel R Browd  2 , Christine L Mac Donald  2 , Monica S Vavilala  1   5 , Frederick P Rivara  1   6
Affiliations

Prevalence of Abnormal Magnetic Resonance Imaging Findings in Children with Persistent Symptoms after Pediatric Sports-Related Concussion

Robert H Bonow et al. J Neurotrauma. .

Abstract

A subset of patients experience persistent symptoms after pediatric concussion, and magnetic resonance imaging (MRI) is commonly used to evaluate for pathology. The utility of this practice is unclear. We conducted a retrospective cohort study to describe the MRI findings in children with concussion. A registry of all patients seen at our institution from January 2010 through March 2016 with pediatric sports-related concussion was cross-referenced with a database of radiographical studies. Radiology reports were reviewed for abnormal findings. Patients with abnormal computed tomographies or MRI scans ordered for reasons other than concussion were excluded. Among 3338 children identified with concussion, 427 underwent MRI. Only 2 (0.5%) had findings compatible with traumatic injury, consisting in both of microhemorrhage. Sixty-one patients (14.3%) had abnormal findings unrelated to trauma, including 24 nonspecific T2 changes, 15 pineal cysts, eight Chiari I malformations, and five arachnoid cysts. One child underwent craniotomy for a cerebellar hemangioblastoma after presenting with ataxia; another had cortical dysplasia resected after seizure. The 2 patients with microhemorrhage each had three previous concussions, significantly more than patients whose scans were normal (median, 1) or abnormal without injury (median, 1.5; p = 0.048). MRI rarely revealed intracranial injuries in children post-concussion, and the clinical relevance of these uncommon findings remains unclear. Abnormalities unrelated to trauma are usually benign. However, MRI should be thoughtfully considered in children who present with concerning or atypical symptoms.

Keywords: brain concussion; magnetic resonance imaging; post-concussion syndrome.

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Conflict of interest statement

R.H.B. received indirect salary support through an educational grant provided to the University of Washington Department of Neurological Surgery by Codman Neuro. S.R.B. has ownership in Aqueduct Neurosciences Inc, Aqueduct Critical Care Inc, and Navisonics Inc. C.L.M. has provided paid consulting services for Neurotrauma Sciences, LLC, and Sinapis Pharma, Inc. These commercial entities had no role in the design, conduct, or reporting of this research.

Figures

<b>FIG. 1.</b>
FIG. 1.
Representative slices from SWI sequences in the 2 patients with microhemorrhage. (A) A solitary focus of SWI hypointensity was observed in the white matter of the left frontal lobe in a 15-year-old male football player 27 days after sustaining a concussion in the course of play. (B) Six foci of SWI hypointensity were observed in this 17-year-old male 10 days after sustaining a concussion during a soccer match; shown here is the finding in the left frontal lobe. SWI, susceptibility-weighted imaging.
See this image and copyright information in PMC

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