Micronutrient powders to combat anemia in young children: does it work?
- PMID: 28490333
- PMCID: PMC5425983
- DOI: 10.1186/s12916-017-0867-8
Micronutrient powders to combat anemia in young children: does it work?
Abstract
In developing countries, anemia and iron deficiency in early childhood are two highly prevalent public health problems. Providing caregivers with a powder containing multiple vitamins and minerals (also known as micronutrient powder or MNP) as a food supplement is a widely used strategy to combat these problems. However, concerns exist around MNP programs with regards to effectiveness and potential negative impact on diarrheal disease prevalence and gut flora. Teshome et al. (BMC Medicine 15:89, 2017) recently tested a MNP with a new iron formulation, iron-EDTA, which has a potentially higher bioavailability and thus requires a lower iron content. Nevertheless, neither the new formulation nor the standard formulation decreased anemia prevalence as compared to a control MNP without iron. However, in all groups, anemia prevalence was reduced after 30 days of intervention, and iron deficiency prevalence was significantly lower in children receiving iron-EDTA, showing that the new formulation holds promise. More research is needed to verify whether the lower iron content of these MNPs can also reduce the prevalence of associated side effects.Please see related article: https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-017-0839-z .
Keywords: Anemia; Infants; Inflammation; Iron deficiency; Micronutrient powder.
Comment in
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Micronutrient powders to combat anaemia in young children: do they work?BMC Med. 2018 Jan 22;16(1):7. doi: 10.1186/s12916-017-0998-y. BMC Med. 2018. PMID: 29353552 Free PMC article.
Comment on
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Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children.BMC Med. 2017 Apr 28;15(1):89. doi: 10.1186/s12916-017-0839-z. BMC Med. 2017. PMID: 28449690 Free PMC article. Clinical Trial.
References
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- Teshome EM, Andang’o PEA, Osoti V, Terwel SR, Otieno W, Demir AY, Prentice AM, Verhoef H. Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children. BMC Med. 2017;15:89. doi: 10.1186/s12916-017-0839-z. - DOI - PMC - PubMed
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- Wieringa FT, Dahl M, Chamnan C, Poirot E, Kuong K, Sophonneary P, Sinuon M, Greuffeille V, Hong R, Berger J. The high prevalence of anemia in Cambodian children and women cannot be satisfactorily explained by nutritional deficiencies or hemoglobin disorders. Nutrients. 2016;8:348. doi: 10.3390/nu8060348. - DOI - PMC - PubMed
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