HIV-associated anaerobes ferment TB risk

Affiliations

Comment

Jennifer A Philips. Sci Transl Med. 2017.

. 2017 May 10;9(389):eaan3781.

doi: 10.1126/scitranslmed.aan3781.

¹ Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. Email: philips.j.a@wustl.edu.

Abstract

Short-chain fatty acids produced by anaerobic bacteria increase the risk of TB in HIV-infected, antiretroviral drug-treated people.

Anaerobic Bacterial Fermentation Products Increase Tuberculosis Risk in Antiretroviral-Drug-Treated HIV Patients.
Segal LN, Clemente JC, Li Y, Ruan C, Cao J, Danckers M, Morris A, Tapyrik S, Wu BG, Diaz P, Calligaro G, Dawson R, van Zyl-Smit RN, Dheda K, Rom WN, Weiden MD. Segal LN, et al. Cell Host Microbe. 2017 Apr 12;21(4):530-537.e4. doi: 10.1016/j.chom.2017.03.003. Epub 2017 Mar 30. Cell Host Microbe. 2017. PMID: 28366509 Free PMC article.