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Case Reports
. 2017 Feb 24;12(2):273-277.
doi: 10.1016/j.radcr.2017.01.018. eCollection 2017 Jun.

Serous cystadenocarcinoma of the spleen

Chung Kuao Chou  1 , Shih-Cheng Chou  2
Affiliations
Case Reports

Serous cystadenocarcinoma of the spleen

Chung Kuao Chou et al. Radiol Case Rep. .

Abstract

The commonly seen primary malignant neoplasms of the spleen are angiosarcoma and lymphoma. We present a case of serous cystadenocarcinoma of the spleen. It was presumed to be originated from dropped nonmalignant ovarian tissue, which was accidentally implanted to the splenic surface during hysterectomy and bilateral salpingooophorectomies for torsion of right fallopian tube 9 and half years ago and transformed into serous cystadenocarcinoma later. Computed tomography demonstrated a multilocular predominantly cystic tumor with internal soft tissue components in the spleen.

Keywords: CT; Serous cystadenocarcinoma; Spleen.

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Figures

Fig. 1
Fig. 1
(A) Postcontrast axial image and (B) postcontrast reformatted coronal image. A multilocular predominantly cystic tumor with relatively smooth tumor wall (arrows) and internal soft tissue components (arrowheads) was seen.
Fig. 2
Fig. 2
The gross specimen showed the cystic tumor wall (arrows), internal soft tissue components (arrowheads), and a mixture of blood and necrotic tissue (BN).
Fig. 3
Fig. 3
(A) A 40× microscopic picture showed neoplastic cells arranged in a papillary pattern. Multiple psammoma bodies (arrows) were seen. (B) A 400× microscopic picture showed clusters of moderately differentiated neoplastic cells bearing hyperchromatic and pleomorphic nuclei, prominent nucleoli, and eosinophilic cytoplasm. (C) The immunohistochemical stain demonstrated diffuse cytoplasmic CK7 expression. (D) The immunohistochemical stain did not demonstrate CK20 expression.
See this image and copyright information in PMC

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