Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 Jun 6;1(5):285-289.
doi: 10.1016/j.hrcr.2015.02.013. eCollection 2015 Sep.

Ventricular fibrillation in lone atrial fibrillation as clinical manifestation of latent Brugada syndrome: Usefulness of flecainide testing

Carlo Pappone  1 , Gabriele Vicedomini  1 , Andrea Petretta  1 , Luigi Giannelli  1 , Amarild Cuko  1 , Vincenzo Santinelli  1
Affiliations
Case Reports

Ventricular fibrillation in lone atrial fibrillation as clinical manifestation of latent Brugada syndrome: Usefulness of flecainide testing

Carlo Pappone et al. HeartRhythm Case Rep. .
No abstract available

Keywords: AF, atrial fibrillation; Atrial fibrillation; BrS, Brugada syndrome; Brugada syndrome; EPT, electrophysiologic testing; Flecainide; ICD, implantable cardioverter-defibrillator; Sudden death; VF, ventricular fibrillation; VT, ventricular tachycardia; Ventricular fibrillation.

PubMed Disclaimer

Figures

Figure 1
Figure 1
A: Baseline 12-lead ECG shows no abnormality. B: After flecainide testing, a coved ST-segment elevation in leads V1–V2 compatible with a type I Brugada syndrome ECG pattern was evident.
Figure 2
Figure 2
Programmed ventricular stimulation resulted in concomitant development of ventricular fibrillation (VF) and atrial fibrillation (AF). VF lasted 7 seconds and spontaneously reverted to sustained AF. The paper speeds are as follows: A: 16 mm/s; B: 25 mm/s.
Figure 3
Figure 3
Twelve-lead ECG after electrophysiologic testing showing a stable sinus rhythm with coved Brugada syndrome pattern.
See this image and copyright information in PMC

References

    1. Francis J., Antzelevitch C. Atrial fibrillation and Brugada syndrome. J Am Coll Cardiol. 2008;51:1149–1153. - PMC - PubMed
    1. Brugada P., Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. J Am Coll Cardiol. 1992;20:1391–1396. - PubMed
    1. Bordachar P., Reuter S., Garrigue S., Caï X., Hocini M., Jaïs P., Haïssaguerre M., Clementy J. Incidence, clinical implications and prognosis of atrial arrhythmias in Brugada syndrome. Eur Heart J. 2004;25:879–884. - PubMed
    1. Ackerman M.J., Priori S.G., Willems S. HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA) Heart Rhythm. 2011;8:1308–1339. - PubMed
    1. Pappone C., Radinovic A., Manguso F. New-onset atrial fibrillation as first clinical manifestation of latent Brugada syndrome: prevalence and clinical significance. Eur Heart J. 2009;30:2985–2992. - PubMed

Publication types

LinkOut - more resources