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Case Reports
. 2015 Dec 18;2(2):128-131.
doi: 10.1016/j.hrcr.2015.10.011. eCollection 2016 Mar.

Familial long QT syndrome and late development of dilated cardiomyopathy in a child with a KCNQ1 mutation: A case report

Kiona Y Allen  1 , Victoria L Vetter  1 , Maully J Shah  1 , Matthew J O'Connor  1
Affiliations
Case Reports

Familial long QT syndrome and late development of dilated cardiomyopathy in a child with a KCNQ1 mutation: A case report

Kiona Y Allen et al. HeartRhythm Case Rep. .
No abstract available

Keywords: Dilated cardiomyopathy; Familial long QT syndrome; Genetics; KCNQ1; Voltage-gated potassium channel.

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Figures

Figure 1
Figure 1
A: Twelve-lead electrocardiogram obtained at 2 days of life showing a corrected QT interval of 495 msec and nonspecific T wave abnormalities. B: Twelve-lead electrocardiogram obtained at time of presentation with heart failure at 9 years of age demonstrating new T wave changes and voltage criteria for left ventricular hypertrophy.
Figure 2
Figure 2
Transthoracic echocardiogram showing severe dilation and systolic dysfunction of the left ventricle.
Figure 3
Figure 3
Family pedigree demonstrating mutations in the KCNQ1 and titin genes. The KCNQ1 was inherited maternally and multiple first- and second-degree relatives were affected, including a maternal cousin with sudden cardiac death. The titin gene mutation was inherited paternally and no other overlap with the KCNQ1 gene was identified.
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