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Review
. 2015 Feb 26;1(1):4-12.
doi: 10.1016/j.ijwd.2015.01.002. eCollection 2015 Feb.

Autoimmune blistering diseases in females: a review

Cathy Y Zhao  1 , Dédée F Murrell  1
Affiliations
Review

Autoimmune blistering diseases in females: a review

Cathy Y Zhao et al. Int J Womens Dermatol. .

Abstract

The autoimmune blistering diseases (AIBDs) are a group of heterogeneous skin diseases with autoantibodies directed against structural proteins in the skin. A new interest in the female bias towards autoimmune diseases in general has led to our attention to focus on how and why this female bias manifests in AIBD. The authors aim to review and explore the various aspects of AIBD affecting females more than males, including the higher prevalence, worse quality of life, and complex management issues such as pregnancy and lactation.

Keywords: Autoimmune blistering diseases; Epidemiology; Epidermolysis bullosa acquisita; Female; Pemphigoid; Pemphigus; Quality of life; Toxic epidermal necrolysis; Treatment.

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Figures

Fig. 1
Fig. 1
Debilitating shallow oral erosions in a female patient with pemphigus vulgaris.
Fig. 2
Fig. 2
Exfoliative scales and erosions on the chest of a female patient with pemphigus foliaceus.
Fig. 3
Fig. 3
Urticarial papules and plaques in a female patient with newly diagnosed bullous pemphigoid.
Fig. 4
Fig. 4
Vesicles and bullae in the gingiva of a female patient with mucous membrane pemphigoid.
Fig. 5
Fig. 5
Urticarial plaques and grouped vesicles on the lower leg of a pregnant woman with pemphigoid gestationis.
Fig. 6
Fig. 6
Annular plaques with raised and eroded margins in a female patient with linear IgA disease.
See this image and copyright information in PMC

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