[Therapy of AIDS]

Abstract

Therapeutic strategies in the management of AIDS should aim at an inhibition of the replication and spread of HIV; the reconstitution of immune functions; an effective chemotherapy of opportunistic infections and tumors; and the prevention of new opportunistic infections. At present, these goals can be only partially achieved and where beneficial therapeutic results are obtained they are only transient in nature. Antiretroviral therapy and chemotherapy of infections have, however, resulted in some, albeit temporary, improvement of the prognosis of ARC/AIDS patients. This review summarizes the principles and results of antiretroviral treatment of the HIV infection and chemotherapy of opportunistic infections in AIDS.