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Review
. 2017 Spring;12(2):123-130.
doi: 10.22037/iej.2017.26.

Effect of Corticosteroids on Pain Relief Following Root Canal Treatment: A Systematic Review

Foad Iranmanesh  1 , Masoud Parirokh  2 , Ali Akbar Haghdoost  3 , Paul V Abbott  4
Affiliations
Review

Effect of Corticosteroids on Pain Relief Following Root Canal Treatment: A Systematic Review

Foad Iranmanesh et al. Iran Endod J. 2017 Spring.

Abstract

Introduction: Post-operative pain and flare-up may occur in up to 58% of patients following root canal treatment. The aim was to conduct a systematic review and a possible meta-analysis to determine the effect of glucocorticosteroid (GCS) on pain following root canal treatment.

Methods and materials: Scopus, MEDLINE and CENTRAL databases were searched up to 30th January 2017 with broad key words. In addition, the reference lists in eligible papers and text books were hand-searched. Assessment of the eligibility of papers and data extraction were performed by two independent reviewers.

Results: Of 9891 articles, 18 were recruited as eligible papers. Most of these papers showed pain reducing effect of GCS on post-endodontic pain. Because of wide heterogeneity among the recruited papers, it was not possible to perform meta-analysis.

Conclusion: Based on the results of this systematic review, there is a vast heterogeneity amongst articles regarding the use of GCS and their effect on post-operative pain after endodontic treatment. Further investigations with similar methods and materials are needed before meta-analysis on the effect of GCS on post-operative pain following root canal treatment can be performed.

Keywords: Corticosteroid; Endodontics; Flare-Up; Meta-Analysis; Post-Operative Pain; Systematic Review.

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Conflict of interest statement

‘None declared’.

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References

    1. Kakoei S, Parirokh M, Nakhaee N, Jamshid Shirazi F, Rad M, Kakooei S. Prevalence of toothache and associated factors: A population-based study in southeast Iran. Iran Endod J. 2013;8(3):123–8. - PMC - PubMed
    1. Parirokh M, Eghbal MJ, Ghoddusi J, Kakoei S, Haghdoost AA, Kakooei S. The frequency of medically compromised patients in endodontic offices in Iran. Iran Endod J. 2013;8(2):48–51. - PMC - PubMed
    1. Lin CS, Wu SY, Yi CA. Association between anxiety and pain in dental treatment. J Dent Res. 2017;96(2):153–162. - PubMed
    1. Parirokh M, Satvati SA, Sharifi R, Rekabi AR, Gorjestani H, Nakhaee N, Abbott PV. Efficacy of combining a buccal infiltration with an inferior alveolar nerve block for mandibular molars with irreversible pulpitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(3):468–73. - PubMed
    1. Parirokh M, Ashouri R, Rekabi AR, Nakhaee N, Pardakhti A, Askarifard S, Abbott PV. The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis. J Endod. 2010;36(9):1450–4. - PubMed

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