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Review
. 2012 Apr 14;4(6):435.
doi: 10.4022/jafib.435. eCollection 2012 Apr-May.

Cardiac Resynchronization Therapy in Patients with Atrial Fibrillation - Worth the Effort?

António M Ferreira  1 , Pedro Carmo  1 , Pedro Adragão  1
Affiliations
Review

Cardiac Resynchronization Therapy in Patients with Atrial Fibrillation - Worth the Effort?

António M Ferreira et al. J Atr Fibrillation. .

Abstract

Congestive heart failure (CHF) and atrial fibrillation (AF) are two increasingly common conditions that predispose to each other and frequently coexist. Cardiac resynchronization therapy(CRT) has emerged as an important therapeutic modality for selected patients with end-stage CHF. However, despite the high prevalence of AF in patients eligible for CRT, almost all the randomized clinical trials that validated the benefit of resynchronization therapy excluded patients with preexisting AF. In this review, we examine the available evidence on the benefits and limitations of CRT in patients with AF and discuss recent data that narrowed the knowledge gap on this topic.

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References

    1. McAlister Finlay A, Ezekowitz Justin, Hooton Nicola, Vandermeer Ben, Spooner Carol, Dryden Donna M, Page Richard L, Hlatky Mark A, Rowe Brian H. Cardiac resynchronization therapy for patients with left ventricular systolic dysfunction: a systematic review. JAMA. 2007 Jun 13;297 (22):2502–14. - PubMed
    1. Maisel William H, Stevenson Lynne Warner. Atrial fibrillation in heart failure: epidemiology, pathophysiology, and rationale for therapy. Am. J. Cardiol. 2003 Mar 20;91 (6A):2D–8D. - PubMed
    1. Dickstein Kenneth, Bogale Nigussie, Priori Silvia, Auricchio Angelo, Cleland John G, Gitt Anselm, Limbourg Tobias, Linde Cecilia, van Veldhuisen Dirk J, Brugada Josep. The European cardiac resynchronization therapy survey. Eur. Heart J. 2009 Oct;30 (20):2450–60. - PubMed
    1. Fein Adam S, Wang Yongfei, Curtis Jeptha P, Masoudi Frederick A, Varosy Paul D, Reynolds Matthew R. Prevalence and predictors of off-label use of cardiac resynchronization therapy in patients enrolled in the National Cardiovascular Data Registry Implantable Cardiac-Defibrillator Registry. J. Am. Coll. Cardiol. 2010 Aug 31;56 (10):766–73. - PMC - PubMed
    1. Wang Thomas J, Larson Martin G, Levy Daniel, Vasan Ramachandran S, Leip Eric P, Wolf Philip A, D'Agostino Ralph B, Murabito Joanne M, Kannel William B, Benjamin Emelia J. Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study. Circulation. 2003 Jun 17;107 (23):2920–5. - PubMed

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