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Review
. 2017 Oct 26;28(7):811-823.
doi: 10.1515/revneuro-2016-0083.

Interactions between cannabis and schizophrenia in humans and rodents

Ahmed A Moustafa  1 , Mohamed Salama  1 , Roseanne Peak  1 , Richard Tindle  1 , Amir Salem  1 , Szabolcs Keri  1 , Błażej Misiak  1 , Dorota Frydecka  1 , Wael Mohamed  1
Affiliations
Review

Interactions between cannabis and schizophrenia in humans and rodents

Ahmed A Moustafa et al. Rev Neurosci. .

Abstract

In this review, we provide an overview of the relationship between cannabis use and the development of schizophrenia, using both animal and human studies. We further discuss the potential neural mechanism that may mediate the relationship between cannabis use and schizophrenia symptoms. We finally provide clinical implications and future studies that can further elucidate the relationship between cannabis and schizophrenia.

Keywords: cannabis; endocannabinoid receptors; negative symptoms; positive symptoms; schizophrenia.

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