Recent Advances in Magnetic Resonance Imaging Assessment of Renal Fibrosis
- PMID: 28501077
- PMCID: PMC5433256
- DOI: 10.1053/j.ackd.2017.03.005
Recent Advances in Magnetic Resonance Imaging Assessment of Renal Fibrosis
Abstract
CKD is a global public health problem. Renal fibrosis is a final common pathway leading to progressive loss of function in CKD. The degree of renal fibrosis predicts the prognosis of CKD. Recent studies have shown that bone marrow-derived fibroblasts contribute significantly to the development of renal fibrosis, which may yield novel therapeutic strategy for fibrotic kidney disease. Therefore, it is imperative to accurately assess the degree of renal fibrosis noninvasively to identify those patients who can benefit from antifibrotic therapy. In this review, we summarize recent advances in the assessment of renal fibrosis by magnetic resonance imaging.
Keywords: Chronic kidney disease; Extracellular matrix; Fibroblast; Fibrosis; Magnetic resonance imaging.
Published by Elsevier Inc.
Conflict of interest statement
The authors have declared that no conflict of interest exists.
Similar articles
-
Multiparametric magnetic resonance imaging of experimental chronic kidney disease: A quantitative correlation study with histology.PLoS One. 2018 Jul 16;13(7):e0200259. doi: 10.1371/journal.pone.0200259. eCollection 2018. PLoS One. 2018. PMID: 30011301 Free PMC article.
-
Value of multiparametric magnetic resonance imaging for evaluating chronic kidney disease and renal fibrosis.Eur Radiol. 2023 Aug;33(8):5211-5221. doi: 10.1007/s00330-023-09674-1. Epub 2023 May 6. Eur Radiol. 2023. PMID: 37148348
-
Could MRI Be Used To Image Kidney Fibrosis? A Review of Recent Advances and Remaining Barriers.Clin J Am Soc Nephrol. 2017 Jun 7;12(6):1019-1028. doi: 10.2215/CJN.07900716. Epub 2017 Mar 15. Clin J Am Soc Nephrol. 2017. PMID: 28298435 Free PMC article. Review.
-
Intravoxel incoherent motion diffusion-weighted imaging for the assessment of renal fibrosis of chronic kidney disease: A preliminary study.Magn Reson Imaging. 2018 Apr;47:118-124. doi: 10.1016/j.mri.2017.12.010. Epub 2017 Dec 5. Magn Reson Imaging. 2018. PMID: 29217491
-
Advances in imaging techniques to assess kidney fibrosis.Ren Fail. 2023 Dec;45(1):2171887. doi: 10.1080/0886022X.2023.2171887. Ren Fail. 2023. PMID: 36723057 Free PMC article. Review.
Cited by
-
Magnetic Resonance Elastography of kidneys: SE-EPI MRE reproducibility and its comparison to GRE MRE.NMR Biomed. 2019 Nov;32(11):e4141. doi: 10.1002/nbm.4141. Epub 2019 Jul 22. NMR Biomed. 2019. PMID: 31329347 Free PMC article.
-
Multiparametric magnetic resonance imaging of experimental chronic kidney disease: A quantitative correlation study with histology.PLoS One. 2018 Jul 16;13(7):e0200259. doi: 10.1371/journal.pone.0200259. eCollection 2018. PLoS One. 2018. PMID: 30011301 Free PMC article.
-
Does Early Diabetic Kidney Damage Alter Renal Elasticity? An Ultrasound-Based, Two-Dimensional Shear Wave Elastography Study.Medeni Med J. 2021;36(3):209-216. doi: 10.5222/MMJ.2021.65021. Epub 2021 Sep 30. Medeni Med J. 2021. PMID: 34915678 Free PMC article.
-
Magnetic resonance diffusion tensor imaging is superior to arterial spin labeling in detecting renal allograft fibrosis.Quant Imaging Med Surg. 2025 Apr 1;15(4):3211-3221. doi: 10.21037/qims-24-1023. Epub 2025 Mar 14. Quant Imaging Med Surg. 2025. PMID: 40235790 Free PMC article.
-
The utility of magnetic resonance imaging for noninvasive evaluation of diabetic nephropathy.Nephrol Dial Transplant. 2020 Jun 1;35(6):970-978. doi: 10.1093/ndt/gfz066. Nephrol Dial Transplant. 2020. PMID: 31329940 Free PMC article.
References
-
- Meguid El Nahas A, Bello AK. Chronic kidney disease: the global challenge. Lancet. 2005;365:331–340. - PubMed
-
- Zeisberg M, Neilson EG. Mechanisms of tubulointerstitial fibrosis. J Am Soc Nephrol. 2010;21:1819–1834. - PubMed
-
- Nath KA. Tubulointerstitial changes as a major determinant in the progression of renal damage. American journal of kidney diseases: the official journal of the National Kidney Foundation. 1992;20:1–17. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical