Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Jun;31(3):389-408.
doi: 10.1016/j.hoc.2017.01.002. Epub 2017 Mar 22.

The Gastric Microbiome and Its Influence on Gastric Carcinogenesis: Current Knowledge and Ongoing Research

Chao Zhang  1 , Sarah Ellen Powell  2 , Doron Betel  1 , Manish A Shah  3
Affiliations
Review

The Gastric Microbiome and Its Influence on Gastric Carcinogenesis: Current Knowledge and Ongoing Research

Chao Zhang et al. Hematol Oncol Clin North Am. 2017 Jun.

Abstract

Gastric malignancies are a leading cause of cancer-related death worldwide. At least 2 microbial species are currently linked to carcinogenesis and the development of cancer within the human stomach. These include the bacterium Helicobacter pylori and the Epstein-Barr virus. In recent years, there has been increasing evidence that within the human gastrointestinal tract it is not only pathogenic microbes that impact human health but also the corresponding autochthonous microbial communities. This article reviews the gastrointestinal microbiome as it relates primarily to mechanisms of disease and carcinogenesis within the upper gastrointestinal tract.

Keywords: EBV; Gastric cancer; Gastric microbiome; Helicobacter pylori; Microbial identification.

PubMed Disclaimer

MeSH terms

LinkOut - more resources