Eosinophilic Gastrointestinal Disorders

Abstract

Eosinophilic esophagitis (EoE) is an atopic disease that is characterized by an isolated infiltration of eosinophils into the epithelium of the esophagus and is triggered by specific allergens. Patients should undergo an upper endoscopy with biopsy after 6 to 8 weeks of treatment with a proton pump inhibitor in order to make the diagnosis of EoE. Eosinophilic gastroenteritis is a pathologic eosinophilic infiltration of any portion of the gastrointestinal tract, and eosinophilic proctocolitis is an eosinophilic infiltration in the colon alone.

Keywords: Eosinophilic esophagitis; Eosinophilic gastroenteritis; Eosinophilic proctocolitis; Food allergens; Proton pump inhibitor-responsive esophageal eosinophilia.