[Quantitative patterns of tubocurarine action on the synaptic potentials of frog muscle]
[Article in
Russian]
- PMID: 2850942
Item in Clipboard
[Quantitative patterns of tubocurarine action on the synaptic potentials of frog muscle]
[Article in
Russian]
Fiziol Zh SSSR Im I M Sechenova.
1988 Sep.
Abstract
The dependence of amplitude of synaptic potentials (EPP and mEPP) upon the d-tubocurarine concentration was studied in the frog cutaneous pectoral muscle. In the presence of d-tubocurarine up to 5 x 10(-7) M, the amplitude of EPP and mEPP decreased to the extent which strictly followed competitive action of d-tubocurarine. At a higher concentration, the inhibition of synaptic potentials was stronger than would be expected assuming that d-tubocurarine can only act as a competitive antagonist.
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