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Multicenter Study
. 2018 Aug 17;7(3):249-252.
doi: 10.1093/jpids/pix034.

Invasive Pneumococcal Disease in Infants Aged 0-60 Days in the United States in the 13-Valent Pneumococcal Conjugate Vaccine Era

Liset Olarte  1 , William J Barson  2 , John S Bradley  3 , Tina Q Tan  4 , Philana Ling Lin  5 , José R Romero  6 , Laurence B Givner  7 , Jill A Hoffman  8 , Kristina G Hultén  1 , Edward O Mason  1 , Sheldon L Kaplan  1
Affiliations
Multicenter Study

Invasive Pneumococcal Disease in Infants Aged 0-60 Days in the United States in the 13-Valent Pneumococcal Conjugate Vaccine Era

Liset Olarte et al. J Pediatric Infect Dis Soc. .

Abstract

We identified 53 infants aged 0-60 days with invasive pneumococcal disease (IPD) at 8 children's hospitals in the United States (2005-2015). After the introduction of 13-valent pneumococcal conjugate vaccine (PCV13), IPD caused by PCV13 serotypes decreased ~30% providing some evidence of indirect protection. However, approximately 60% of IPD was still caused by PCV13 serotypes.

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