Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Apr;65(4):318-320.
doi: 10.4103/ijo.IJO_683_16.

Combination of phototherapeutic keratectomy and wavefront-guided photorefractive keratectomy for the treatment of Thiel-Behnke corneal dystrophy

Affiliations
Case Reports

Combination of phototherapeutic keratectomy and wavefront-guided photorefractive keratectomy for the treatment of Thiel-Behnke corneal dystrophy

Chia-Chieh Hsiao et al. Indian J Ophthalmol. 2017 Apr.

Abstract

Phototherapeutic keratectomy (PTK) has been used to treat anterior corneal dystrophy but may cause hyperopic shift or corneal high-order aberration. We describe the successful treatment of a case of a 43-year-old female with Thiel-Behnke corneal dystrophy, using PTK followed by wavefront-guided photorefractive keratectomy (PRK). The patient had high corneal aberration and hyperopic shift after PTK in both eyes. The corneal surface regularity index and surface asymmetric index increased after PTK and decreased after wavefront-guided PRK. Vision improved from preoperative 20/400 and 20/60 to postoperative 20/20 and 20/25 in the right eye and the left eye, respectively. Additional wavefront-guided PRK may enhance the effects of PTK by reducing irregular corneal surfaces and by correcting PTK-induced hyperopic shift.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a and b) Slit-beam photography and the insets demonstrate superficial honeycomb opacities in both eyes. (c and d) Corneal opacities much decreased after phototherapeutic keratectomy. (e and f) Less opacity was left after subsequent wavefront-guided photorefractive keratectomy
Figure 2
Figure 2
Corneal topography. (a and b) Mild irregular surface in both corneas. (c and d) Irregularity of corneal surface increased after phototherapeutic keratectomy. (e and f) Corneal surface became smooth and regular after wavefront-guided photorefractive keratectomy

Similar articles

Cited by

References

    1. Munier FL, Korvatska E, Djemaereste Paslier D, Zografos L, Pescia G, et al. Kerato-epithelin mutations in four 5q31-linked corneal dystrophies. Nat Genet. 1997;15:247–51. - PubMed
    1. Seitz B, Lisch W. Stage-related therapy of corneal dystrophies. Dev Ophthalmol. 2011;48:116–53. - PubMed
    1. Hieda O, Kawasaki S, Wakimasu K, Yamasaki K, Inatomi T, Kinoshita S. Clinical outcomes of phototherapeutic keratectomy in eyes with Thiel-Behnke corneal dystrophy. Am J Ophthalmol. 2013;155:66–72.e1. - PubMed
    1. Hou YC, Hsiao CH, Kuo KT, Wang IJ, Hu FR. TGFBI-linked corneal dystrophies treated using superficial lamellar keratectomy combined with phototherapeutic keratectomy. Eye (Lond) 2012;26:170–2. - PMC - PubMed
    1. Hou YC, Wang IJ, Hsiao CH, Chen WL, Hu FR. Phenotype-genotype correlations in patients with TGFBI-linked corneal dystrophies in Taiwan. Mol Vis. 2012;18:362–71. - PMC - PubMed

Publication types

Supplementary concepts