You Can Breathe Easy: IFNλ Handles Flu without Triggering a Damaging Inflammatory Response
- PMID: 28514682
- DOI: 10.1016/j.immuni.2017.04.027
You Can Breathe Easy: IFNλ Handles Flu without Triggering a Damaging Inflammatory Response
Abstract
Type III interferon (IFNλ) and type I IFN (IFNα/β) have overlapping antiviral activities in the lung. In this issue of Immunity, Galani et al. (2017) identify a critical early role for IFNλ, not shared by IFNα/β, in protection of the lung following influenza virus infection.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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  Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness.Immunity. 2017 May 16;46(5):875-890.e6. doi: 10.1016/j.immuni.2017.04.025. Immunity. 2017. PMID: 28514692
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