Dengue Antibodies, then Zika: A Fatal Sequence in Mice
- PMID: 28514683
- DOI: 10.1016/j.immuni.2017.04.023
Dengue Antibodies, then Zika: A Fatal Sequence in Mice
Abstract
Anti-Dengue virus (DENV) antibodies can be either protective or pathogenic in humans with prior DENV infection. In a recent issue of Science, Bardina et al. (2017) demonstrated that passive transfer of immune plasma against DENV and West Nile virus (WNV) can enhance Zika virus (ZIKV) infection and pathogenesis in mice.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
-
Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity.Science. 2017 Apr 14;356(6334):175-180. doi: 10.1126/science.aal4365. Epub 2017 Mar 30. Science. 2017. PMID: 28360135 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical