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Comment
. 2017 May 16;46(5):771-773.
doi: 10.1016/j.immuni.2017.04.023.

Dengue Antibodies, then Zika: A Fatal Sequence in Mice

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Dengue Antibodies, then Zika: A Fatal Sequence in Mice

Jonathan J Miner et al. Immunity. .
Free article

Abstract

Anti-Dengue virus (DENV) antibodies can be either protective or pathogenic in humans with prior DENV infection. In a recent issue of Science, Bardina et al. (2017) demonstrated that passive transfer of immune plasma against DENV and West Nile virus (WNV) can enhance Zika virus (ZIKV) infection and pathogenesis in mice.

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